Adsense ,Tips for Earning maximum Money from Google Adsense

1. If your site have specific useful topic with properly matched theme, then it ranked higher place in search engines as well as will get the best revenue out of Adsense if the topics targeted have sufficient number of ads available.
2. First target is reduced moderate or low paying keywords as your specific topic. Sites targeting highest paying keywords will find better responced.
3. For relevant ads best choice is use older websites have better clicks. Older websites generally will rank better in search engines and generate better ads revenue simply because and the ads will become more relevant .
4. If you use more than one website then use Tracking Channels. It help to understand best performing sites, and to study the ads that make the most money in Google Adsense program, and ads placement. Compare results on a weekly basis to see what ads work best.
5. It's best that ads links should be different from the content colors to increase click. Blend ads with site content . For e.g. create ads without borders close to content. If your site get same readers repeatedly then randomizing ads link colors frequently is also a good practice so that frequent readers don't filter the ads of Adsense program.
6. The value per ads decreases as you increase the number of ads displayed. up to a max of three ads units .To serve the most high paying ads on your site, compromise with the number of ads displayed and decreased the number of ads displayed.
7. According to Google Adsense ads placed on hot spots and without scrolling will generate higher click-throughs . Based on this hot spots map, the best place is near the beginning of the content, header region, right upper sidebar. 
8. The best ads sizes with highest click are the 336 x 280, the 300 x 250, and the 160 x 600.